My current settings for Microsoft Flight Simulator (MSFS) SU10 Updated

My PC setup

Except the settings below , i have also tuned the colors with NVIDIA Freestyle.

My current rig setup:

CPU: i7-8700k overclocked to 5.0Ghz
GPU: MSI 3070 8GB
RAM: 32GB
HDD: SSD
Resolution: 1440p

Settings

Nvidia Control Panel settings

Disable SHARPEN in Flight Simulator post-process

Flight Simulator post process the image before it is being shown to the screen. These options do not exist in the UI. you can find them in the file UserCfg.opt which is located in the LocalCache directory which can be found in: C:\Users[Your User Name]\AppData\Local\Packages\ Microsoft.FlightSimulator_8wekyb3d8bbwe\LocalCache\Packages\

Make sure Flight Simulator is NOT running.
Open the file UserCfg.opt with a text editor (e.g. Notepad) and navigate to the bottom of the file.
Find the PostProcess section.
Change Sharpen from 1 to 0.
Save the file.
If the value changes after you exit the simulator , then make the file read-only.

Logitech 3D Pro Sensitivity settings

Disable NDU via registry

Open the Registry editor app (Regedit) again and navigate to HKEY_LOCAL_MACHINE/SYSTEM/CurrentControlSet/Services/Ndu.
Find and Right-click on the Start option and click on Modify.
Change the value from 2 to 4 and click on OK and reboot system.

Original post from MSFS forum: LINK